Q

I'm 39 and have been trying to conceive for more than three years. During the cesarean delivery of my first child, my left tube and ovary tore. That tube and ovary (and a cyst on my right ovary) were recently removed. I've been on Clomid for three months and Parlodel (for prolactin) a year. A hysterosalphingogram indicated my right tube was clear, but an x-ray revealed either a fistula or a weakening on the left side of my uterus. What is a fistula and how it can affect pregnancy? Also, are there any long-term effects from the use of Parlodel?



A

A fistula is an abnormal opening or tract between two structures or organs. Fistulas can be caused by infection or trauma such as instrumentation during gynecological or obstetric procedures or by tearing, as with a fistula between the rectum and the vagina after a difficult birth.

In your case, it could be an opening in the uterus or tube. If the uterus itself has a defect within the wall or evidence of an old rupture or perforation, it could put you at risk for ruptured uterus with a pregnancy. This can be minor and cause no problems, but there is a risk of maternal and fetal death.

Consult with a reproductive endocrinologist and make certain that you do find out exactly what kind of fistula you have an where it is before attempting pregnancy and .

Parlodel (or bromocriptine) is used to lower prolactin levels if this has been judged to be a cause of infertility. This drug is used on a long-term basis with people suffering from Parkinson's, and the only reference to long-term side effects that I could find is to watch for shortness of breath from fluid in the lungs (not a common problem).

I hope this helps answer your questions.